DVT, or deep vein thrombosis, is the formation
and release of blood clots (thrombi) inside the deep veins,
most often in the legs. PE (pulmonary embolism) occurs when
one of these thrombi becomes lodged in the lungs. Together,
these conditions are referred to as VTE, or venous thromboembolism.
DVT can cause significant, crippling damage. PE is a life-threatening
event.
Causes
Changes in intrathoracic
pressure associated with anesthesia and surgical procedures
can reduce venous return from the extremities to the heart.
Surgical and therapeutic trauma
can set up a chemical “chain reaction” that causes
proliferation of clotting factors in the deep veins.
And, most importantly: Patient
immobility, for hours, days, or weeks, enhances venous stasis
because the “muscle pump” and “foot pump”
of the legs, which are activated by physical activity, are
in disuse.
The muscle pump and foot pump
Blood flow in the deep veins is significantly
affected by physical activity. The deep veins are surrounded
by muscles that press against the vein walls. As the muscles
contract and extend during normal physical activity, the veins
are compressed, causing the blood inside them to flow towards
the heart. One-way valves inside the veins keep the blood
from moving in the wrong direction.
Two powerful mechanisms for propelling this
venous blood are the calf muscles on the back of the lower
leg (the "muscle pump"), and the vein bed located
on the sole of the foot (the "foot pump"). When
you walk, the veins on the sole of the foot are compressed
and released. This “pumping” action squeezes the
blood inside the veins upwards, to the heart. At the same
time, the powerful muscles on the back of your lower leg contract
and extend, applying and releasing pressure to the veins of
the legs, also propelling the venous flow. In fact, the blood-moving
action of the “muscle pump” is so effective that
this mechanism is often called the “peripheral heart.”

Click the
image above to see how the foot and muscle
pumps work to increase venous blood flow
When a patient is immobile for long periods,
such as during and after surgery, recovering from injury,
or as a result of illness or stroke, the "muscle pump"
and "foot pump" are in disuse. Under these conditions,
venous blood may stagnate in the legs, allowing clots to form.
Other risk factors aside from immobility may further increase
risk of clot formation.
Did you know?
DVT occurs in 2 million Americans each year.
DVT is a major complication in orthopedic surgical patients.
Each year 600,000 patients in the USA develop PE, and 10%
of these will die as a result.
More American women die each year from PE than from breast
cancer!
In the USA, PE is the most frequent cause of death associated
with childbirth!
DVT prevention